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Species of Ephedra have traditionally been used by indigenous people for a variety of medicinal purposes, and are a likely candidate for the Soma plant of Indo-Iranian religion. Also known as ma huang, it was used in traditional Chinese medicine up to 5,000 years ago, probably for the treatment of asthma and hay fever. In the late 1900s, it was used as a stimulant and a dieting aid. Due to the risk of adverse effects on the cardiovascular system, Western medical professionals recommend against the consumption of any ephedra.*

Chemistry


The alkaloids ephedrine and pseudoephedrine are the active constituents of the plant. Pseudoephedrine is used in over-the-counter decongestants. Ephedrine is used to treat low blood pressure, but alternatives with reduced cardiovascular risk have replaced it for treating asthma. It is also considered a performance-enhancing drug and is prohibited in most competitive sports. Some species in the Ephedra genus have zero alkaloid content and are therefore essentially inert, however the most commonly used species, Ephedra sinica, has a total alkaloid content of 1–3% by dry weight. Ephedrine constitutes 40–90% of the alkaloid content, with the remainder consisting of pseudoephedrine and the demethylated forms of each *.

Effects


Ephedra is both a stimulant (similar to adrenaline) and a thermogenic. It stimulates the brain, increases heart rate, constricts blood vessels (increasing blood pressure), and expands bronchial tubes (making breathing easier). Its thermogenic properties cause an increase in metabolism, evidenced by an increase in body heat.

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