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Celecoxib (INN) (IPA: ) is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer under the brand name Celebrex.

Pharmacology


Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits this isoform of cyclooxygenase, whereas traditional NSAIDs inhibit both COX-1 and COX-2. Celecoxib is approximately 10-20 times more selective for COX-2 inhibition over COX-1. In theory, this specificity allows celecoxib and other COX-2 inhibitors to reduce inflammation (and pain) while minimizing gastrointestinal adverse drug reactions (e.g. stomach ulcers) that are common with non-selective NSAIDs. It also means that it has a reduced effect on platelet aggregation compared to traditional NSAIDs.

Adverse effects


Main article: Non-steroidal anti-inflammatory drug

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I hear moaning coming from the bedroom, and not the good kind. gotta go take my wife some celebrex. Hope you never have chronic pain synd
turkfontaine (Wayne Wisecarver) Sat, 07 Nov 2009 05:46:27 -0000
I hear moaning coming from the bedroom, and not the good kind. gotta go take my wife some celebrex. Hope you never have chronic pain synd
Celebrex is workin' ya'll....no bad pains since Wed!! What a relief!! Soooooo glad it's FRIDAY!
PKPastor (Pennie Pastor) Fri, 06 Nov 2009 18:06:15 -0000
Celebrex is workin' ya'll....no bad pains since Wed!! What a relief!! Soooooo glad it's FRIDAY!
Need Class Action Lawyer Contacting a Celebrex Law Firm The Best …: When the full side effects of Pfizer's anti.. http://bit.ly/DnnPf
alfridap (Alfrida Parnell) Thu, 05 Nov 2009 19:15:31 -0000
Need Class Action Lawyer Contacting a Celebrex Law Firm The Best …: When the full side effects of Pfizer's anti.. http://bit.ly/DnnPf
taking Celebrex, day 2, it's helping the pain, so maybe i can deal for a while w/o surgery.
PKPastor (Pennie Pastor) Thu, 05 Nov 2009 14:58:18 -0000
taking Celebrex, day 2, it's helping the pain, so maybe i can deal for a while w/o surgery.
Class Action: Need Class Action Lawyer Contacting a Celebrex Law Firm The Best ... http://bit.ly/20f0Mp
alfridap (Alfrida Parnell) Thu, 05 Nov 2009 11:04:42 -0000
Class Action: Need Class Action Lawyer Contacting a Celebrex Law Firm The Best ... http://bit.ly/20f0Mp
@valeriebianca http://twitpic.com/oc41v - haw babe needs celebrex it was making it better. but for now take those aleve and not just one. i
ralphness (Ralph James Batey) Thu, 05 Nov 2009 07:09:52 -0000
@valeriebianca http://twitpic.com/oc41v - haw babe needs celebrex it was making it better. but for now take those aleve and not just one. i

 
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500 Miles, PC - Discussing possible legal remedies arising from the use of Celebrex.
Meta Description: [ Information on Celebrex Lawsuits and Celebrex Class Actions brought to you by Beasley Allen Law Firm - Experienced celebrex attorneys / celebrex lawyers. ]

Specter, PC - Information on possible Celebrex litigation from a Pennsylvania law firm.
Meta Description: [ Kline & Specter, P.C. - Celebrex injury litigation lawyers representing individuals and their families throughout the United States who have been injured by the side effects of Celebrex. Click here to find a Celebrex Attorney in your state. ]

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