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Isotretinoin (INN) (IPA: ) is a medication used for the treatment of severe acne. It is a retinoid, meaning it is derived from vitamin A and is found in small quantities naturally in the body. Oral isotretinoin is marketed under various trade names, most commonly Accutane or Roaccutane (Roche); while topical isotretinoin is most commonly marketed under the trade names Isotrex or Isotrexin (Stiefel).
History
Prior to the development of isotretinoin, the mainstay treatment of severe acne was oral antibiotics such as the tetracyclines and erythromycin. While these drugs have proven efficacy, they worked against only one contributing factor of acne – the Propionibacterium acnes bacteria. The antibiotics gradually became less effective over time as more resistant strains of the bacterium became prominent.
An early, effective treatment of acne was high doses of the fat-soluble vitamin A. At these dose levels (sometimes 500,000 IU per day) effects such as reduced production of sebum and dry hair could be noticed. However the vitamin also had many other prominent side effects which inhibited its widespread use.
More on [ Isotretinoin ]
New study may deal final blow to acne drug Accutane: (No increased risk was found for Crohn's disease, perh.. http://bit.ly/4FQ9L2
barreto57 (Julio Barreto) Sat, 07 Nov 2009 07:40:15 -0000
New study may deal final blow to acne drug Accutane: (No increased risk was found for Crohn's disease, perh.. http://bit.ly/4FQ9L2
Rt @careforskin New study may deal final blow to acne drug Accutane http://tinyurl.com/yeq3jwl ....another known side-effect to add!!!
SkincareSOS (Lorraine O'Mullane) Sat, 07 Nov 2009 07:24:11 -0000
Rt @careforskin New study may deal final blow to acne drug Accutane http://tinyurl.com/yeq3jwl ....another known side-effect to add!!!
New study may deal final blow to acne drug Accutane http://tinyurl.com/yeq3jwl
careforskin (Care For Your Skin) Sat, 07 Nov 2009 07:14:40 -0000
New study may deal final blow to acne drug Accutane http://tinyurl.com/yeq3jwl
New study may deal final blow to acne drug Accutane http://bit.ly/4FQ9L2
GraceBarkwell (GraceBarkwell) Sat, 07 Nov 2009 06:42:51 -0000
New study may deal final blow to acne drug Accutane http://bit.ly/4FQ9L2
Just saw a commercial for a Drug called accutane saying that if you have certain sypmtoms you've the illness, one was feeling sleepy! What?!
DanielLipscomb (Daniel Lipscomb) Sat, 07 Nov 2009 06:41:28 -0000
Just saw a commercial for a Drug called accutane saying that if you have certain sypmtoms you've the illness, one was feeling sleepy! What?!
Bank_Risk: #risk #management New study may deal final blow to acne drug Accutane - Los Angeles Times: New study may deal http://url4.eu/i2e8
cro_tweets (Chief Risk Officer) Sat, 07 Nov 2009 06:29:56 -0000
Bank_Risk: #risk #management New study may deal final blow to acne drug Accutane - Los Angeles Times: New study may deal http://url4.eu/i2e8
Robichaux Law Firm - Introduction to accutane side effects and litigation.
Meta Description: [ If you believe that you have suffered an injury or illness due to the use of accutane, you may have a claim against the manufacturer or distributor of the drug. ]
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