Addiction is a chronic disorder proposed to be precipitated by a combination of genetic, biological/pharmacological and social factors. Addiction is characterized by the repeated use of substances or behaviors despite clear evidence of morbidity secondary to such use.
There is a lack of consensus as to what may properly be termed 'addiction.' Some within the medical community maintain a rigid definition of addiction and contend that the term is only applicable to a process of escalating drug or alcohol use as a result of repeated exposure. However, addiction is often applied to compulsive behaviors other than drug use, such as overeating or gambling. These behavioral addictions, however, almost never exist without another addiction to some substance . In all cases, the term addiction describes a chronic pattern of behavior that continues and is perceived to be hard or impossible to quit at any time. It is quite common for an addict to express the desire to stop the behavior, but find himself or herself unable to cease.
Addiction is often characterized by an ongoing effort to use more (drug or behavior), tolerance, and withdrawal symptoms in the absence of the stimulus. Many drugs and behaviors that provide either pleasure or relief from pain pose a risk of addiction or dependency.
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Nicotine and Addiction: the Brown and Williamson Documents - Once-secret memos show the tobacco industry had a sophisticated and scientifically accurate understanding of nicotine pharmacology, including an explicit recognition of nicotine's addictiveness, more than 30 years ago.
Meta Description: [ JAMA, the Journal of the American Medical Association, is a highly cited weekly medical journal that publishes peer-reviewed new medical research findings and editorial opinions on a wide variety of topics important to clinical practice and biomedical science. JAMA has the largest circulation of ... ]
Philip Morris Tried to `Bury' Damaging Nicotine Research - News article; secret memos reveal that Philip Morris officials suggested that internal documents about research should be destroyed, and negative information should be kept secret.
Prying Open the Door to the Tobacco Industry's Secrets About Nicotine - AMA scientific article. Tobacco industry documents reveal that for decades, the industry knew and internally acknowledged that nicotine is an addictive drug and cigarettes are the ultimate nicotine delivery device; that nicotine addiction can be perpetuated and even enhanced through cigarette design alterations and manipulations.
Meta Description: [ JAMA, the Journal of the American Medical Association, is a highly cited weekly medical journal that publishes peer-reviewed new medical research findings and editorial opinions on a wide variety of topics important to clinical practice and biomedical science. JAMA has the largest circulation of ... ]
Secrets of BAT Industries - Inside the restricted laboratory compound on the south coast of England, five senior scientists for BAT Industries, the world's second-biggest cigarette maker, were devising ways to make it harder for people to quit smoking...
Secrets of Big Tobacco - News article follows the trial of industry memos that discuss how and why to manipulate cigarette chemistry.
Timeline: Chemical Manipulation of Tobacco Products - Industry documents over time reveal the history of product engineering for addiction.
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Why and How a Cigarette Maker Created a More Addictive Tobacco - Article on tobacco industry research into nicotine and addiction, and RD efforts to engineer more addictive product.
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