Bushmeat (calque from the French viande de brousse) is the term commonly used for meat of terrestrial wild animals, killed for subsistence or commercial purposes throughout the humid tropics of the Americas, Asia and Africa. However, originally the term was only used to describe the hunting of wild animals in West and Central Africa. To reflect the global nature of hunting of wild animals Resolution 2.64 of the IUCN General Assembly in Amman (October 2000) referred to wild meat rather than bushmeat. The term ‘bushmeat crisis’ tends to be used to describe unsustainable hunting of wildlife in West and Central Africa or the humid tropics, depending on interpretation.
HIV-1 is the more virulent and easily transmitted, and is the source of the majority of HIV infections throughout the world; HIV-2 is largely confined to west Africa. Bonobos and chimpanzees from the family Hominidae can be carriers of the HIV-1 and HIV-2 virus without developing AIDS. This puzzles scientists, and many in the scientific community feel if they can figure out why in these primates the HIV virus don't progress into AIDS, that a treatment can be developed. SIV monkey strains are transmitted sexually and usually do not cause disease in their natural hosts. Scientists take this as evidence that host and virus have evolved together for a long time. There is some other mechanism at work in these primates that preventing them from developing AIDS beyond what makes conventional vaccines work in humans. Vaccines work by exposing the body to the proteins on the surface of a virus (which are foreign to the human body), so the body can recognize the foreign invader by these proteins and build up an army antibodies that will re ready to attack the virus when it tries to invade. The HIV virus surrounds its proteins with a layer of simple sugars, which are not foreign to the human body. Thus the body sees no foreign proteins to attack; it only sees non-foreign sugars. Why non-human primates don't develop AIDS is considered the Holy Grail in understanding this disease. Humans often take years to develop AIDS after being infected, so the human immune system does seem to be able to delay the onslaught. The lack of a strong immune response in natural primate hosts appears to spare them from the chronic immune response and subsequent immunopathogenesis observed in humans and non-natural host species. The monkey SIV strains do not infect humans and HIV-1 does not infect monkeys. In 2004, this was explained by different variants of the protein TRIM5α in humans and monkeys. This intracellular protein recognizes the capsid of various retroviruses and blocks their reproduction. To better study HIV/AIDS in animal models, researchers have created various HIV-SIV chimeras, viruses whose genome partly comes from HIV and partly from SIV. These are often referred to as SHIV.
More on [ Bushmeat ]

Bushmeat Crisis Task Force - Documents and bibliography on aspects of the bushmeat trade, and efforts to combat it
Bushmeat Project Bibliography - A working bibliography on hunting and bushmeat commerce in West Central Africa.
Meta Description: [ Bushmeat Project Bibliography ]
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